Faculty Publications

November 2016

British Journal of Hematology

"Inhalation dosimetry modeling provides insights into regional respiratory tract toxicity of inhaled diacetyl.".
Cichocki JA, Morris JB.
Toxicology. 2016 Nov 13. pii: S0300-483X(16)30266-9. doi: 10.1016/j.tox.2016.11.007. [Epub ahead of print].

British Journal of Hematology

"Formulation design space for stable, pH sensitive crystalline nifedipine nanoparticles.".
Jog R, Unachukwu K, Burgess DJ.
Int J Pharm. 2016 Nov 30;514(1):81-92. doi: 10.1016/j.ijpharm.2016.08.039.

British Journal of Hematology


"Recombinant IL-7/HGFβ hybrid cytokine separates acute graft-versus-host-disease from graft-versus-tumour activity by altering donor T cell trafficking".

Hu R, Liu Y, Song Y, Su M, Lu X, Rood D, Lai L.
Br J Haematol. 2016 Nov;175(3):505-516. doi: 10.1111/bjh.14268.

October 2016

British Journal of Hematology


Draft Genome Sequence of Streptomyces sp. AVP053U2 Isolated from Styela clava, a Tunicate Collected in Long Island Sound.

deMayo JA, Maas KR, Klassen JL, Balunas MJ.
Genome Announc. 2016 Oct 13;4(5). pii: e00874-16. doi: 10.1128/genomeA.00874-16.

British Journal of Hematology

Corrigendum to "Triboelectrification: A review of experimental and mechanistic modeling approaches with a special focus on pharmaceutical powders" [Int. J. Pharm. 510 (2016) 375-385].
Naik S, Mukherjee R,Chaudhuri BJ.
Int J Pharm. 2016 Oct 15;512(1):329. doi: 10.1016/j.ijpharm.2016.09.026. No abstract available.

September 2016

journal - international journal of pharmaceutics

Advanced knowledge in drug metabolism and pharmacokinetics.
Yu AM, Zhong XB.
Acta Pharm Sin B . 2016 Sep;6(5):361-362. No abstract available.

journal - international journal of pharmaceutics

Isoniazid metabolism and hepatotoxicity.
Wang P, Pradhan K, Zhong XB.,Ma X.
Acta Pharm Sin B. 2016 Sep;6(5):384-392. Review.

journal - international journal of pharmaceutics

Role of farnesoid X receptor in establishment of ontogeny of phase-I drug metabolizing enzyme genes in mouse liver.
Peng L, Piekos S, Guo GL, Zhong XB.
Acta Pharm Sin B. 2016 Sep;6(5):453-459.

journal - international journal of pharmaceutics

Protein Internal Dynamics Associated With Pre-System Glass Transition Temperature Endothermic Events: Investigation of Insulin and Human Growth Hormone by Solid State Hydrogen/Deuterium Exchange.
Fang R, Grobelny PJ, Bogner RH, Pikal MJ.
J Pharm Sci. 2016 Sep 15. pii: S0022-3549(16)41628-X. doi: 10.1016/j.xphs.2016.07.028. [Epub ahead of print]

British Journal of Hematology

Leisingera sp. JC1, a Bacterial Isolate from Hawaiian Bobtail Squid Eggs, Produces Indigoidine and Differentially Inhibits Vibrios.
Gromek SM, Suria AM, Fullmer MS, Garcia JL, Gogarten JP, Nyholm SV,Balunas MJ.
Front Microbiol. 2016 Sep 8;7:1342. doi: 10.3389/fmicb.2016.01342. eCollection 2016.

British Journal of Hematology

Novel α-substituted tropolones promote potent and selective caspase-dependent leukemia cell apoptosis.
Li J, Falcone ER, Holstein SA, Anderson AC, Wright DL, Wiemer AJ.
Pharmacol Res. 2016 Sep 20. pii: S1043-6618(16)30582-5. doi: 10.1016/j.phrs.2016.09.020. [Epub ahead of print]

British Journal of Hematology

Draft Genome Sequence of Streptomyces sp. Strain PTY087I2, Isolated from Styela canopus, a Panamanian Tunicate.
Gromek SM, Sung AA, Klassen JL, Balunas MJ.
Genome Announc. 2016 Sep 15;4(5). pii: e00856-16. doi: 10.1128/genomeA.00856-16.

British Journal of Hematology

Improving paclitaxel pharmacokinetics by using tumor-specific mesoporous silica nanoparticles with intraperitoneal delivery.
Fu Q, Hargrove D, Lu X.
Nanomedicine. 2016 May 2. pii: S1549-9634(16)30045-4. doi: 10.1016/j.nano.2016.04.013. [Epub ahead of print]

August 2016

journal - nanomedicine

Synthesis and biological evaluation of santacruzamate A analogues for anti-proliferative and immunomodulatory activity.
Gromek SM, deMayo JA, Maxwell AT, West AM, Pavlik CM, Zhao Z, Li J, Wiemer AJ, Zweifach A, Balunas MJ.
Bioorg Med Chem. 2016 Aug 24. pii: S0968-0896(16)30648-4. doi: 10.1016/j.bmc.2016.08.040. [Epub ahead of print]

journal - nanomedicine

Propargyl-Linked Antifolates Are Potent Inhibitors of Drug-Sensitive and Drug-Resistant Mycobacterium tuberculosis.
Hajian B, Scocchera E, Keshipeddy S, G-Dayanandan N, Shoen C, Krucinska J, Reeve S, Cynamon M, Anderson AC, Wright DL.
J Pharm Sci. 2016 Aug 18. pii: S0022-3549(16)41586-8. doi: 10.1016/j.xphs.2016.07.012. [Epub ahead of print]

journal - pharmaceutical science

Development of a Rational Design Space for Optimizing Mixing Conditions for Formation of Adhesive Mixtures for Dry-Powder Inhaler Formulations.
Sarkar S, Minatovicz B, Thalberg K, Chaudhuri B.
J Pharm Sci. 2016 Aug 18. pii: S0022-3549(16)41586-8. doi: 10.1016/j.xphs.2016.07.012. [Epub ahead of print]

journal - nanomedicine

Molecular mechanisms linking geranylgeranyl diphosphate synthase to cell survival and proliferation.
Agabiti SS, Liang Y, Wiemer AJ.
Mol Membr Biol. 2016 Aug 18:1-11. [Epub ahead of print]

journal - nanomedicine

Heat Transfer Analysis of an Optimized, Flexible Holder System for Freeze-Drying in Dual Chamber Cartridges Using Different State-of-the-Art PAT Tools.
Korpus C, Pikal M, Friess W.
J Pharm Sci. 2016 Aug 20. pii: S0022-3549(16)41577-7. doi: 10.1016/j.xphs.2016.07.005. [Epub ahead of print]

July 2016

journal - nanomedicine

Recombinant IL-7/HGFβ hybrid cytokine separates acute graft-versus-host-disease from graft-versus-tumour activity by altering donor T cell trafficking.
Hu R, Liu Y, Song Y, Su M, Lu X, Rood D.
Br J Haematol. 2016 Jul 22. doi: 10.1111/bjh.14268. [Epub ahead of print]

journal - nanomedicine

From hepatoprotection models to new therapeutic modalities for treating liver diseases: a personal perspective.
Rudraiah S., Manautou JE..
Version 2. F1000Res. 2016 Jul 14 [revised 2016 Jul 19];5. pii: F1000 Faculty Rev-1698. doi: 10.12688/f1000research.8609.2. eCollection 2016. Review.

June 2016

ACS Med Chem

Spatial Variation of Pressure in the Lyophilization Product Chamber Part 1: Computational Modeling.
Ganguly A, Varma N, Sane P, Bogner R, Pikal M, Alexeenko A.
AAPS PharmSciTech. 2016 May 5. [Epub ahead of print]

May 2016

journal - aaps pharmscitech

Charged Nonclassical Antifolates with Activity Against Gram-Positive and Gram-Negative Pathogens

Charged Nonclassical Antifolates with Activity Against Gram-Positive and Gram-Negative Pathogens.
Scocchera E, Reeve SM, Keshipeddy S, Lombardo MN, Hajian B, Sochia AE, Alverson JB, Priestley ND, Anderson AC, Wright DL
ACS Med Chem Lett. 2016 May 5;7(7):692-6. doi: 10.1021/acsmedchemlett.6b00120. eCollection 2016 Jul 14

journal - aaps pharmscitech

Spatial Variation of Pressure in the Lyophilization Product Chamber Part 1: Computational Modeling.
Ganguly A, Varma N, Sane P, Bogner R, Pikal M, Alexeenko A.
AAPS PharmSciTech. 2016 May 5. [Epub ahead of print]

April 2016

journal - proteins

Elucidation of the Mechanisms through Which the Reactive Metabolite Diclofenac Acyl Glucuronide Can Mediate Toxicity.
Scialis RJ, Manautou JE.
J Pharmacol Exp Ther. 2016 Apr;357(1):167-76. doi: 10.1124/jpet.115.230755. Epub 2016 Feb 11.

journal - proteins

Computational analysis of the CB1 carboxyl-terminus in the receptor-G protein complex.
Shim JY, Khurana L, Kendall DA.
Proteins. 2016 Apr;84(4):532-543. doi: 10.1002/prot.24999. Epub 2016 Feb 15.

journal - journal of biomedical screening

Development of an Enhanced Phenotypic Screen of Cytotoxic T-Lymphocyte Lytic Granule Exocytosis Suitable for Use with Synthetic Compound and Natural Product Collections.
Zhao Z, deMayo JA, West AM, Balunas MJ, Zweifach A.
J Biomol Screen. 2016 Apr 5. pii: 1087057116643260. [Epub ahead of print]

March 2016

journal - pharmacological research


Interindividual Variability in Cytochrome P450-Mediated Drug Metabolism.

Tracy TS, Chaudhry AS, Prasad B, Thummel KE, Schuetz EG, Zhong XB, Tien YC, Jeong H, Pan X, Shireman LM, Tay-Sontheimer J, Lin YS.
Drug Metab Dispos. 2016 Mar;44(3):343-51. doi: 10.1124/dmd.115.067900. Review.

journal - pharmacological research

Reduced In Vivo Toxicity of Doxorubicin by Encapsulation in Cholesterol-Containing Self-Assembled Nanoparticles.
Gonzalez-Fajardo L, Mahajan LH, Ndaya D, Hargrove D, Manautou JE, Liang BT, Chen MH, Kasi RM, Lu X.
Pharmacol Res. 2016 Mar 11. pii: S1043-6618(16)30180-3. doi: 10.1016/j.phrs.2016.03.006. [Epub ahead of print]

journal - aaps pharmscitech

Spatial Variation of Pressure in the Lyophilization Product Chamber Part 2: Experimental Measurements and Implications for Scale-up and Batch Uniformity.
Sane P, Varma N, Ganguly A, Pikal M, Alexeenko A, Bogner RH.
AAPS PharmSciTech. 2016 Mar 17. [Epub ahead of print]

February 2016

journal - journal of pharmaceutical science

Liposome Formation Using a Coaxial Turbulent Jet in Co-Flow.
Costa AP, Xu X, Khan MA, Burgess DJ.
Pharm Res. 2016 Feb;33(2):404-16. doi: 10.1007/s11095-015-1798-8.

journal - journal of pharmaceutical science

Formulation design and evaluation of amorphous ABT-102 nanoparticles.
Jog R, Kumar S, Shen J, Jugade N, Tan DC, Gokhale R, Burgess DJ.
Int J Pharm. 2016 Feb 10;498(1-2):153-69. doi: 10.1016/j.ijpharm.2015.12.033

journal - journal of pharmaceutical science

Crystal Structures of Trimethoprim-Resistant DfrA1 Rationalize Potent Inhibition by Propargyl-Linked Antifolates.
Lombardo MN, G-Dayanandan N, Wright DL, Anderson AC.
ACS Infect Dis. 2016 Feb 12;2(2):149-56. doi: 10.1021/acsinfecdis.5b00129. Epub 2016 Jan 4.

journal - journal of pharmaceutical science

Addition of Monovalent Electrolytes to Improve Storage Stability of Freeze-Dried Protein Formulations.
Goshima H, Forney-Stevens KM, Liu M, Qian KK, Tyagi M, Cicerone MT, Pikal MJ.
J Pharm Sci. 2016 Feb;105(2):530-41. doi: 10.1016/j.xphs.2015.10.004. Epub 2015 Dec 30.

journal - chemmedchem

Synthesis and Evaluation of Osteogenic Oxysterols as Hedgehog Pathway Activators.
Maschinot CA, Corman AR, DeBerardinis AM, Hadden MK.
ChemMedChem. 2016 Feb 25. doi: 10.1002/cmdc.201500550.

journal - pharmacological research

Acetaminophen; From Liver to Brain: New Insights into Drug Pharmacological Action and Toxicity.
Ghanem CI, Pérez MJ, Manautou JE, Mottino AD.
Pharmacol Res. 2016 Feb 24. pii: S1043-6618(16)00053-0. doi: 10.1016/j.phrs.2016.02.020.

journal - journal of pharmaceutical science

Quantification of Tribocharging of Pharmaceutical Powders in V-Blenders: Experiments, Multiscale Modeling, and Simulations.
Naik S, Hancock B, Abramov Y, Yu W, Rowland M, Huang Z, Chaudhuri B.
J Pharm Sci. 2016 Feb 23. pii: S0022-3549(15)00254-3. doi: 10.1016/j.xphs.2015.12.024.

journal - journal of biomedical screening

Flow Cytometry Enables Multiplexed Measurements of Genetically Encoded Intramolecular FRET Sensors Suitable for Screening.
Doucette J, Zhao Z, Geyer RJ, Barra MM, Balunas MJ, Zwei-fach A.
J Biomol Screen. 2016 Feb 23. pii: 1087057116634007.

journal - osteoarthritis and cartilage

Epigenetically Mediated Spontaneous Reduction of NFAT1 Expression Causes Imbalanced Metabolic Activities of Articular Chondrocytes in Aged Mice.
Zhang M, Lu Q, Egan B, Zhong XB, Brandt K, Wang J.
Osteoarthritis Cartilage. 2016 Feb 18. pii: S1063-4584(16)01024-4. doi: 10.1016/j.joca.2016.02.003.

journal - journal of ethnopharmacology

Current Therapeutic Role and Medicinal Potential of Scutellaria barbata in Traditional Chinese Medicine and Western Research.
Tao G, Balunas MJ.
J Ethnopharmacol. 2016 Feb 10. pii: S0378-8741(16)30053-8. doi: 10.1016/j.jep.2016.02.012.

journal - biochimica et biophysica acta

Enhanced hepatotoxicity by acetaminophen in vanin-1 knockout mice is associated with deficient proliferative and immune responses.
Ferreira DW, Goedken MJ, Rommelaere S, Chasson L, Galland F, Naquet P, Manautou JE.
Biochim Biophys Acta. 2016 Feb 2. pii: S0925-4439(16)30027-8. doi: 10.1016/j.bbadis.2016.02.001.

January 2016

journal - scientific reports nature

"http://www.ncbi.nlm.nih.gov/pubmed/26633590"Computational Prediction and Biochemical Analyses of New Inverse Agonists for the CB1 Receptor..
Scott CE, Ahn KH, Graf ST, Goddard WA 3rd, Kendall DA, Abrol R.
J Chem Inf Model. 2016 Jan 25;56(1):201-12. doi: 10.1021/acs.jcim.5b00581.

journal - scientific reports nature

A Biocompatible and Biodegradable Protein Hydrogel with Green and Red Auto-fluorescence: Preparation, Characteri-za-tion and In Vivo Biodegradation Tracking and Mode-ling.
Ma X, Sun X, Hargrove D, Chen J, Song D, Dong Q, Lu X, Fan TH, Fu Y, Lei Y.
Sci Rep. 2016 Jan 27;6:19370. doi: 10.1038/srep19370.

journal - organic letters

Medusamide A, a Panamanian Cyanobacterial Depsipeptide with Multiple β-Amino Acids.
Fenner AM, Engene N, Spadafora C, Gerwick WH, Balunas MJ.
Org Lett. 2016 Jan 19. [Epub ahead of print]

December 2015

journal - drug metabolism and disposition

Dose of Phenobarbital and Age of Treatment at Early Life are Two Key Factors for the Persistent Induction of Cytochrome P450 Enzymes in Adult Mouse Liver.
Tien YC, Liu K, Pope C, Wang P, Ma X, Zhong XB.
Drug Metab Dispos. 2015 Dec;43(12):1938-45. doi: 10.1124/dmd.115.066316. Epub 2015 Sep 23.

journal - drug metabolism and disposition

Green tea extract provides extensive Nrf2-independent protection against lipid accumulation and NFκB pro- inflammatory responses during nonalcoholic steatohepatitis in mice fed a high-fat diet.
Li J, Sapper TN, Mah E, Rudraiah S, Schill KE, Chitchumroonchokchai C, Moller MV, McDonald JD, Rohrer PR, Manautou JE, Bruno RS.
Mol Nutr Food Res. 2015 Dec 17. doi: 10.1002/mnfr.201500814. [Epub ahead of print]

journal - international journal of pharmaceutics

Formulation design and evaluation of amorphous ABT-102 nanoparticles.
Jog R, Kumar S, Shen J, Jugade N, Tan DC, Gokhale R, Burgess DJ.
Int J Pharm. 2015 Dec 15. pii: S0378-5173(15)30433-6. doi: 10.1016/j.ijpharm.2015.12.033. [Epub ahead of print]

journal - vitamins and hormones

Hedgehog and Vitamin D Signaling Pathways in Development and Disease.
Hadden MK.
Vitam Horm. 2016;100:231-53. doi: 10.1016/bs.vh.2015.10.006. Epub 2015 Dec 17.

November 2015

journal - drug metabolism and disposition

Advances in Inhalation Dosimetry Models and Methods for Occupational Risk Assessment and Exposure Limit Derivation.
Kuempel ED, Sweeney LM,Morris JB, Jarabek AM.
J Occup Environ Hyg. 2015;12 Suppl 1:S18-40. doi: 10.1080/15459624.2015.1060328.

journal - drug metabolism and disposition

Evaluation of a 7-Methoxycoumarin-3-carboxylic Acid Ester Derivative as a Fluorescent, Cell-Cleavable, Phosphonate Protecting Group.
Wiemer AJ, Shippy RR, Kilcollins AM, Li J, Hsiao CH, Barney RJ, Geng ML, Wiemer DF.
Chembiochem. 2016 Jan 1;17(1):52-5. doi: 10.1002/cbic.201500484. Epub 2015 Nov 19.

journal - drug metabolism and disposition

Redox-Sensitive Nanoparticles from Amphiphilic Cholesterol-Based Block Copolymers for Enhanced Tumor Intracellular Release of Doxorubicin.
Nguyen CT, Tran TH, Lu X, Kasi RM.
Nanomedicine: Nanotechnology, Biology, and Medicine. 2015, 11(8): 2071–2082.

journal - drug metabolism and disposition

Oxidative stress-responsive transcription factor NRF2 is not indispensable for the human hepatic Flavin-containing monooxygenase-3 (FMO3) gene expression in HepG2 cells.
Rudraiah S, Gu X, Hines RN, Manautou JE.
Toxicol In Vitro. 2015 Nov 23. pii: S0887-2333(15)30017-5. doi: 10.1016/j.tiv.2015.11.016. [Epub ahead of print]

journal - journal of medicinal food

Blue-Green Algae Inhibit the Development of Atherosclerotic Lesions in Apolipoprotein E Knockout Mice.
Ku CS, Kim B, Pham TX, Yang Y, Wegner CJ, Park YK, Balunas M, Lee JY.
J Med Food. 2015 Nov 13. [Epub ahead of print]

journal - future microbiology

The challenge of resistance in antimicrobial drug development.
Anderson AC, Wright DL.
Future Microbiol. 2015 Nov;10:1709-10. doi: 10.2217/fmb.15.75. No abstract available.

October 2015

journal - future microbiology

Understanding the structural mechanisms of antibiotic resistance sets the platform for new discovery.
Reeve SM, Lombardo MN, Anderson AC.
Future Microbiol. 2015 Nov;10:1727-33. doi: 10.2217/fmb.15.78. Epub 2015 Oct 30.

journal - plos one

Deciphering the Developmental Dynamics of the Mouse Liver Transcriptome.
Gunewardena SS, Yoo B, Peng L, Lu H, Zhong X, Klaassen CD, Cui JY.
PLoS One. 2015 Oct 23;10(10):e0141220. doi: 10.1371/journal.pone.0141220. eCollection 2015.

journal - environmental health perspectives

Effect of Acetaminophen on Oxidant and Irritant Respiratory Tract Responses to Environmental Tobacco Smoke in Female Mice.
Smith GJ, Cichocki JA, Doughty BJ, Manautou JE, Jordt SE, Morris JB.
Environ Health Perspect. 2015 Oct 9. [Epub ahead of print]

journal - international journal of cell biology

Liposome Formation Using a Coaxial Turbulent Jet in Co-Flow.
Costa AP, Xu X, Khan MA, Burgess DJ.
Pharm Res. 2015 Oct 1. [Epub ahead of print].

September 2015

journal - journal of pharmaceutical science

Addition of Amino Acids to Further Stabilize Lyophilized Sucrose-Based Protein Formulations: I. Screening of 15 Amino Acids in Two Model Proteins.
Forney-Stevens KM, Bogner RH, Pikal MJ.
J Pharm Sci. 2015 Sep 28. doi: 10.1002/jps.24655. [Epub ahead of print]

journal - drug metabolism and disposition

Dose of Phenobarbital and Age of Treatment at Early Life are Two Key Factors for the Persistent Induction of Cytochrome P450 Enzymes in Adult Mouse Liver.
Tien YC, Liu K, Pope C, Wang P, Ma X, Zhong XB.
Drug Metab Dispos. 2015 Dec;43(12):1938-45. doi: 10.1124/dmd.115.066316. Epub 2015 Sep 23.

journal - international journal of cell biology

Carboxymethyl Hyaluronan-Stabilized Nanoparticles for Anticancer Drug Delivery.
Woodman JL, Suh MS, Zhang J, Kondaveeti Y, Burgess DJ, White BA, Prestwich GD, Kuhn LT.
Int J Cell Biol. 2015;2015:249573. doi: 10.1155/2015/249573. Epub 2015 Sep 10.

August 2015

journal - archives in biochemistry and biophysics

Functional importance of a peripheral pocket in mammalian cytochrome P450 2B enzymes.
Jang HH, Liu J, Lee GY, Halpert JR, Wilderman PR.
Arch Biochem Biophys. 2015 Oct 15;584:61-9. doi: 10.1016/j.abb.2015.08.007. Epub 2015 Aug 28.

journal - journal of diabetes science and technology

Foreign Body Reaction to Implantable Biosensors: Effects of Tissue Trauma and Implant Size.
Wang Y, Vaddiraju S, Gu B, Papadimitrakopoulos F, Burgess DJ.
J Diabetes Sci Technol. 2015 Aug 25;9(5):966-77. doi: 10.1177/1932296815601869.

journal - cell stress chaperones

Antioxidant fractions of Khaya grandifoliola C.DC. and Entada africana Guill. et Perr. induce nuclear translocation of Nrf2 in HC-04 cells.
Njayou FN, Amougou AM, Fouemene Tsayem R, Njikam Manjia J, Rudraiah S, Bradley B, Manautou JE, Fewou Moundipa P.
Cell Stress Chaperones. 2015 Nov;20(6):991-1000. doi: 10.1007/s12192-015-0628-6. Epub 2015 Aug 14.

journal - molecular pharmaceutics

Drug Distribution in Microspheres Enhances Their Anti-Inflammatory Properties in the Gottingen Minipig.
Kastellorizios M, Tipnis N, Papadimitrakopoulos F, Burgess DJ.
Mol Pharm. 2015 Sep 8;12(9):3332-8. doi: 10.1021/acs.molpharmaceut.5b00326. Epub 2015 Aug 10.

journal - journal of organic chemistry

Bastimolide A, a Potent Antimalarial Polyhydroxy Macrolide from the Marine Cyanobacterium Okeania hirsuta.
Shao CL, Linington RG, Balunas MJ, Centeno A, Boudreau P, Zhang C, Engene N, Spadafora C, Mutka TS, Kyle DE, Gerwick L, Wang CY, Gerwick WH.
J Org Chem. 2015 Aug 21;80(16):7849-55. doi: 10.1021/acs.joc.5b01264. Epub 2015 Aug 5.

July 2015

journal - journal of controlled release

Multiple tissue response modifiers to promote angiogenesis and prevent the foreign body reaction around subcutaneous implants.
Kastellorizios M, Papadimitrakopoulos F, Burgess DJ.
J Control Release. 2015 Sep 28;214:103-11. doi: 10.1016/j.jconrel.2015.07.021. Epub 2015 Jul 26.

journal - nanomedicine

Redox-sensitive nanoparticles from amphiphilic cholesterol-based block copolymers for enhanced tumor intracellular release of doxorubicin.
Nguyen CT, Tran TH, Amiji M, Lu X, Kasi RM.
Nanomedicine. 2015 Nov;11(8):2071-82. doi: 10.1016/j.nano.2015.06.011. Epub 2015 Jul 11.

journal - journal of the american chemical society

Nonracemic Antifolates Stereoselectively Recruit Alternate Cofactors and Overcome Resistance in S. aureus.
Keshipeddy S, Reeve SM, Anderson AC, Wright DL.
J Am Chem Soc. 2015 Jul 22;137(28):8983-90. doi: 10.1021/jacs.5b01442. Epub 2015 Jul 8..

journal - drug metabolism and disposition

Multidrug Resistance-Associated Protein 3 Plays an Important Role in Protection against Acute Toxicity of Diclofenac.
Scialis RJ, Csanaky IL, Goedken MJ, Manautou JE..
Drug Metab Dispos. 2015 Jul;43(7):944-50. doi: 10.1124/dmd.114.061705. Epub 2015 Apr 20.