Photo of Brian Aneskievich

Brian Aneskievich

  • E-Mail
  • Phone
    • (860) 486-3053
  • Fax
    • (860) 486-5792
  • Office
    • School of Pharmacy
      Room 536
  • Mail
    • University of Connecticut
      Dept. of Pharmaceutical Sciences
      69 North Eagleville Road
      Storrs, CT 06269-3092

Associate Professor of Pharmacology & Toxicology

Educational Background

  • B.S. Pennsylvania State University, Cell Biology
  • Ph.D. State University of New York at Stony Brook, Cell & Developmental Biology
  • Postdoctoral Training: University of Pennsylvania, Cell & Molecular Biology
  • Postdoctoral Training: University of Chicago, Howard Hughes Medical Institute, Molecular Biology

Research Interests

  • Molecular pharmacology of nuclear receptor activation and moderation by coregulatory proteins
  • Transcriptional and cell biological consequences of nuclear receptor activity
  • Epidermal skin cell growth and differentiation regulation relevant to aging, carcinogenesis and wound healing
  • Moderation of post-receptor (membrane and nuclear) signaling pathways leading to chronic inflammatory states

Selected Publications

  • Ramirez, V.P., W. Krueger, B.J. Aneskievich. 2015. TNIP1 reduction of HSPA6 gene expression occurs in promoter regions lacking binding sites for known TNIP1-repressed transcription factors. Gene. 555: 430-437. Recommended as being of special significance in its field by Faculty of 1000
  • Ramirez, V.P., M. Stamatis, A. Shmukler, and B.J. Aneskievich. 2015. Basal and stress inducible expression of HSPA6 in human keratinocytes is regulated by negative and positive promoter regions. Cell Stress & Chaperones. 20: 95-107.
  • Gurevich, I., Zhang, C., Francis, N., Struzynsky, C.P., Livings, S.E., Aneskievich, B.J. 2013. Human TNFα-induced protein 3-interacting protein 1 (TNIP1) promoter activation is regulated by retinoic acid receptors, Gene 515, 42–48.
  • Ramirez, V.P., Gurevich, I. and Aneskievich, B.J. 2012. Emerging roles for TNIP1 in regulating post-receptor signaling, Cytokine & Growth Factor Reviews 23, 109–118.
  • Zhang, C., Gurevich, I., Aneskievich, B.J. 2012. Organotypic modeling of human keratinocyte response to peroxisome proliferators, Cells, Tissues, Organs 196, 431–41.
  • Gurevich, I., Zhang, C., Encarnacao, P.C., Struzynski, C.P., Livings, S.E. and Aneskievich, B.J. 2012. PPARγ and NF-κB regulate the gene promoter activity of their shared repressor, TNIP1, Biochimica et Biophysica Acta: Gene Regulatory Mechanisms 1819, 1-15.