Debra Kendall

Board of Trustees

Distinguished Professor of Medicinal Chemistry

Department of Pharmaceutical Sciences


Educational Background

  • B.A. Smith College, Biochemistry
  • Ph.D. Northwestern University, Biochemistry
  • Postdoctoral Training: Rockefeller University

Research Interests

  • Biochemical and biophysical analyses of membrane-interactive proteins
  • Cannabinoid receptor activation and signal transduction
  • Allosteric modulation of GPCRs including biased signaling outcomes

Selected Publications

  • C. Nogueras-Ortiz,  Roman-Vendrell, C., Mateo-Semidey, G.E., Liao, Y.-H. Kendall, D.A., and Yudowski, G.A. (2017) Retromer stops beta-arrestin 1 mediated signaling from internalized cannabinoid 2 receptors, Mol. Biol. Cell,  doi:10.1091/mbc.E17-03-0198.
  • Khurana, L., Fu, B., Duddupudi, A., Liao, Y.-H., Immadi, S. S., Kendall, D.A. Lu, D. (2017)    Pyrimidinyl Biphenylureas: Identification of New Lead Compounds as Allosteric Modulators of the Cannabinoid Receptor CB1. J. Med. Chem., 60, 1089-1104.
  • Kendall, D.A. and Yudowski, G.A. (2017) Cannabinoid Receptors in the Central Nervous System: Their Signaling and Roles in Disease. Front. Cell. Neurosci. 10, 294.
  • Qiao C.-J,. Ali, H.I., Ahn, K.H., Kolluru, S., Kendall, D.A. and Lu, D. (2016) Synthesis and Biological Evaluation of Indole-2-carboxamides Bearing Photoactivatable Functionalities as Novel Allosteric Modulators for the Cannabinoid CB1 Receptor. Eur. J. Med. Chem. 121, 517-529.
  • Delgado-Peraza, F., Ahn, K.H., Nogueras-Ortiz, C., Mungrue, I. Mackie, K.P., Kendall, D.A. and Yudowski, G.A. (2016) Mechanisms of Biased Beta-arrestin Mediated Signaling Downstream from the Cannabinoid 1 Receptor. Mol. Pharmacol. 89, 645-651.
  • Shim, J.-Y., Khurana, L. and Kendall, D.A. (2016) Computational Analysis of the CB1 Carboxyl-terminus in the Receptor-G Protein Complex. Proteins: Struct. Funct. Bioinf. 84, 532-543.
Contact Information
Emaildebra.kendall@uconn.edu
Phone(860) 486-1891
Fax(860) 486-6857
Mailing Address69 North Eagleville Road
Unit 3092
Storrs, Connecticut 06269-3092
Office LocationSchool of Pharmacy, Room 638
CampusStorrs
Linkhttp://kendalllab.uconn.edu/