Recent publications
- Clinical Profile and Treatment Adherence in Patients with Type 2 Diabetes and Chronic Kidney Disease Who Initiate an SGLT2 Inhibitor: A Multi-cohort Study December 17, 2024CONCLUSIONS: At a 1-year follow-up, at least half of the patients with CKD and T2D were receiving SGLT2i treatment across the data sources. In patients initiating SGLT2i, treatment options for T2D and CKD were heterogeneous and dynamic within and among data sources.Catherine B Johannes
- COEPA ready: Innovative pedagogy for integrating social determinants of health in PharmD curricula December 15, 2024CONCLUSION: These exemplars provide faculty with varied models for implementing SDH-related teaching opportunities within their institutions.Jennifer Bhuiyan
- Clinical outcomes of a twice daily metronidazole dosing strategy for Bacteroides bloodstream infections December 12, 2024CONCLUSIONS: In the largest study to date of patients with Bacteroides spp. bacteremia treated with metronidazole, twice daily dosing strategies were not associated with worse outcomes compared to thrice daily metronidazole dosing strategies.Sunish Shah
- Pharmacists as Partners in Pediatric Immunizations: A White Paper From the Pediatric Pharmacy Association December 11, 2024No abstractJennifer E Girotto
- Burden of Hospitalization for Coccidioidal Meningitis: An Analysis of the National Inpatient Sample, 2019-2021 December 11, 2024Coccidioidal meningitis (CM) requires lifelong aggressive management, often necessitating hospitalization. In the National Inpatient Sample (2019-2021), CM hospitalizations (N = 2305) were associated with frequent CM-related procedures (63.6% [95% confidence interval {CI}, 59.3%-67.6%]), long stays (mean, 13.0 days [95% CI, 11.3-14.6 days]), substantial costs per stay (mean, $48 155 [95% CI, $42 382-$53 929]), and […]Craig I Coleman
- Prescription for Curricular Revision: Application of Design Thinking Principles November 25, 2024Continuous quality improvement of the professional curriculum can present as a series of complex problems to solve. Schools and colleges of pharmacy would benefit from a structured framework to approach complex problem-solving while engaging faculty and students throughout the process. Design thinking is a framework that promotes creative problem-solving while using techniques that make ambiguity […]Diana M Sobieraj
- Meta-analysis of predictors of healthcare-associated <em>Clostridioides difficile</em> infection November 20, 2024Our systematic review and meta-analysis of 40 studies (n = 3,905,559) identified gastric acid suppressants, recent hospitalization, antibiotic exposure, and certain comorbidities as independent predictors of healthcare-associated Clostridioides difficile infection (HA-CDI) among adult inpatients. Targeted antibiotic stewardship and judicious use of gastric acid suppressants can reduce the incidence of HA-CDI.Jesse Fajnzylber
- Donor pulmonary hemodynamics does not impact recipient outcomes in adult heart transplantation November 18, 2024CONCLUSIONS: Donor pulmonary pressures did not impact post-heart transplant survival in adult recipients. Donors with abnormal pulmonary hemodynamics remain viable donor hearts for transplantation.Zeina Jedeon
- Determining Ideal Practices for Student Course Evaluations Using a Modified Delphi Approach November 16, 2024CONCLUSION: This Delphi study established consensus on approaches programs can use to optimize SCEs, according to experts from across the academy. Though some items are very specific, there are opportunities for individualization based on program priorities.Aleda M H Chen
- Canadian Spine Society: 24th Annual Scientific Conference, Wednesday, February 28 - Saturday, March 2, Fairmont Chateau Whistler, Whistler, B.C., Canada November 13, 2024No abstractAntoine Dionne
- Management of factor Xa inhibitor-related traumatic non-intracranial bleeding events with andexanet alfa or four-factor prothrombin complex concentrate in a US multicenter observational study November 11, 2024CONCLUSION: This analysis provides insights into the clinical characteristics and management strategies, including time to treatment, for patients treated with andexanet alfa or 4F-PCC while hospitalized for FXa inhibitor-related traumatic bleeds.Paul P Dobesh
- Sex Disparities in the Use and Outcomes of Septal Reduction Therapies for Obstructive Hypertrophic Cardiomyopathy November 11, 2024CONCLUSIONS: Our results suggest that female patients were slightly more likely to undergo SRT, especially alcohol septal ablation. In-hospital mortality and postprocedural complications were similar between the sexes, but women received more pacemaker implantation and less ICD implantation.Carlos Diaz-Arocutipa
- A systematic review of reporting and handling of missing data in observational studies using the UNOS database November 9, 2024CONCLUSIONS: Merely a third of the identified UNOS database studies reported how they handled missing data in their analysis, with strategies varying. Although no singular approach to handling missing data exists, methods are available that can improve upon the most used approaches. Future best practices should include explicit reporting of missingness, detailed methods, and sensitivity […]William L Baker
- Falls and fractures in men with prostate cancer taking second-generation androgen receptor antagonists: A retrospective chart review October 22, 2024CONCLUSION: The prevalence of falls and fractures in patients receiving enzalutamide were higher in this retrospective chart review than reported in clinical trials and post-marketing studies. This could be due to the small patient population or the patient's comorbidities such as osteoporosis, bone metastases, or neuropathy. Fall/fracture risk with enzalutamide and other risk factors for […]Morgan Dennison
- Triglyceride-glucose index as a predictor of cardiac adverse events in acute coronary syndrome patients undergoing percutaneous coronary intervention: role of diabetes September 28, 2024CONCLUSION: Based on our findings, while higher TyG levels and quartiles were associated with higher rates of MACCE in ACS, there was no such effect in the euglycemic population. If confirmed in future studies, these results can be beneficial for clinicians to risk stratify these patients with an easy-to-use index and determine clinical plans based […]Amirmohammad Khalaji
- Bypassing Prescribers and Pharmacists: Online Purchasing of Semaglutide and Tirzepatide "For Research Purposes" September 17, 2024Unscrupulous manufacturers provide consumers with ways to circumvent access controls by purchasing drug products outside the legitimate prescription drug supply chain. Manufacturers are selling vials containing semaglutide and tirzepatide to consumers without a prescription for "research purposes only" and/or "not for human consumption," but frequently without the supplies and knowledge they would need to dissolve […]Jordyn Belcourt
- Exploring Tools to Manage Curricular Content and Overload Within the Professional PharmD Program August 30, 2024CONCLUSIONS: Established tools, such as the ACCP Pharmacotherapy Didactic Curriculum Toolkit, are helpful in selecting curricular topics, but additional guidance is needed to optimize its usefulness in managing curricular overload. Developing toolkits for foundational sciences, SAS, and top 200/300 medications is necessary to provide similar guidance for the Academy.Diana M Sobieraj
- Antithrombotic Strategies for Patients With Peripheral Artery Disease: JACC Scientific Statement August 28, 2024Patients with peripheral artery disease (PAD) experience major cardiovascular and limb events. Antithrombotic strategies including antiplatelets and anticoagulants remain a cornerstone of treatment and prevention. Recent trials have shown heterogeneity in the response to antithrombotic therapies in patients presenting primarily with PAD when compared to those presenting primarily with coronary artery disease. In addition, there […]Marc P Bonaca
- The Role of Pediatric Pharmacists in the Prevention and Treatment of Congenital Syphilis August 15, 2024In recent years, rates of syphilis in adults have been on the rise resulting in an increase in the number of neonates born with congenital syphilis. National organizations including the Centers for Disease Control and Prevention as well as The US Preventative Services Task Force recommend routine testing of pregnant persons to identify and provide […]Taylor Barnes
- Exploring the harm reduction paradigm: the role of Board-Certified Psychiatric Pharmacists August 6, 2024Deaths related to opioid overdoses continue to climb, and there remains a need for innovative strategies to address this ongoing crisis. Harm reduction (HR), a nonjudgmental philosophy aimed at reducing consequences associated with drug use and other potentially unsafe behavior, has emerged as a compassionate and effective approach. Harm reduction further emphasizes overdose prevention and […]Amber R Douglass