Recent publications
- Prognostic Value of Frailty in Patients With Takotsubo Cardiomyopathy January 16, 2025CONCLUSIONS: Our results suggest that frailty is useful as a prognostic factor for in-hospital events in patients with TCM.Carlos Diaz-Arocutipa
- Diagnostic models to differentiate Takotsubo syndrome from acute coronary syndrome: A systematic review and meta-analysis January 14, 2025CONCLUSION: Our review identified multiple diagnostic models to diagnose Takotsubo syndrome. Although most models showed acceptable-to-good discriminative performance, calibration measures were almost unreported and the risk of bias was a concern in most studies.Carlos Diaz-Arocutipa
- Effect of Mediterranean Diets on Cardiovascular Risk Factors and Disease in Overweight and Obese Adults: A Systematic Review and Meta-Analysis of Randomized Controlled Trials January 9, 2025We systematically evaluated effects of Mediterranean diets (MED) on cardiovascular (CV) disease and risk factors in overweight or obese adults. Five engines and two registries were searched until October 2023 for randomized controlled trials (RCTs) evaluating any type of MED compared to other diets or advice in adults. Outcomes of interest were clinical outcomes and […]Adrian V Hernandez
- Assessing the Alignment Between Pharmacists' Reported Tasks and Employer-Advertised Skills January 1, 2025CONCLUSION: The fact that prescription review remains the top task from O*NET over the past 10 years and the top advertised skill in Lightcast is patient care underscores the contemporary misalignment and highlights a potential discrepancy in the emphasis of pharmacy education.Amy L Ives
- Examining the Alignment of Pharmacists' Daily Tasks, Employer-advertised Skills, and the Entrustable Professional Activities January 1, 2025CONCLUSION: Prescription processing, legal compliance, and operational pharmacy management are the most essential daily functions of today's pharmacists, contrasting with the person-centered nature of the EPAs. Amid the curricular evolution that has occurred to meet the future vision of pharmacy practice, programs must, nonetheless, continue to teach the skills required for the existing marketplace to […]Diana M Sobieraj
- Real-World Antifungal Therapy Patterns Across the Continuum of Care in United States Adults with Invasive Aspergillosis December 27, 2024Changes to antifungal therapy (AFT) in invasive aspergillosis (IA) may occur due to intolerance, side effects, drug interactions, or lack of response. We describe AFT change patterns in IA patients. This was a US claims data study. IA patients were identified during the index hospitalization from October 2015 to November 2022. Patients were stratified by […]Barbara D Alexander
- Clinical Profile and Treatment Adherence in Patients with Type 2 Diabetes and Chronic Kidney Disease Who Initiate an SGLT2 Inhibitor: A Multi-cohort Study December 17, 2024CONCLUSIONS: At a 1-year follow-up, at least half of the patients with CKD and T2D were receiving SGLT2i treatment across the data sources. In patients initiating SGLT2i, treatment options for T2D and CKD were heterogeneous and dynamic within and among data sources.Catherine B Johannes
- COEPA ready: Innovative pedagogy for integrating social determinants of health in PharmD curricula December 15, 2024CONCLUSION: These exemplars provide faculty with varied models for implementing SDH-related teaching opportunities within their institutions.Jennifer Bhuiyan
- Clinical outcomes of a twice daily metronidazole dosing strategy for Bacteroides bloodstream infections December 12, 2024CONCLUSIONS: In the largest study to date of patients with Bacteroides spp. bacteremia treated with metronidazole, twice daily dosing strategies were not associated with worse outcomes compared to thrice daily metronidazole dosing strategies.Sunish Shah
- Burden of Hospitalization for Coccidioidal Meningitis: An Analysis of the National Inpatient Sample, 2019-2021 December 11, 2024Coccidioidal meningitis (CM) requires lifelong aggressive management, often necessitating hospitalization. In the National Inpatient Sample (2019-2021), CM hospitalizations (N = 2305) were associated with frequent CM-related procedures (63.6% [95% confidence interval {CI}, 59.3%-67.6%]), long stays (mean, 13.0 days [95% CI, 11.3-14.6 days]), substantial costs per stay (mean, $48 155 [95% CI, $42 382-$53 929]), and […]Craig I Coleman
- Pharmacists as Partners in Pediatric Immunizations: A White Paper From the Pediatric Pharmacy Association December 11, 2024No abstractJennifer E Girotto
- Prescription for Curricular Revision: Application of Design Thinking Principles November 25, 2024Continuous quality improvement of the professional curriculum can present as a series of complex problems to solve. Schools and colleges of pharmacy would benefit from a structured framework to approach complex problem-solving while engaging faculty and students throughout the process. Design thinking is a framework that promotes creative problem-solving while using techniques that make ambiguity […]Diana M Sobieraj
- Meta-analysis of predictors of healthcare-associated <em>Clostridioides difficile</em> infection November 20, 2024Our systematic review and meta-analysis of 40 studies (n = 3,905,559) identified gastric acid suppressants, recent hospitalization, antibiotic exposure, and certain comorbidities as independent predictors of healthcare-associated Clostridioides difficile infection (HA-CDI) among adult inpatients. Targeted antibiotic stewardship and judicious use of gastric acid suppressants can reduce the incidence of HA-CDI.Jesse Fajnzylber
- Donor pulmonary hemodynamics does not impact recipient outcomes in adult heart transplantation November 18, 2024CONCLUSIONS: Donor pulmonary pressures did not impact post-heart transplant survival in adult recipients. Donors with abnormal pulmonary hemodynamics remain viable donor hearts for transplantation.Zeina Jedeon
- Determining Ideal Practices for Student Course Evaluations Using a Modified Delphi Approach November 16, 2024CONCLUSION: This Delphi study established consensus on approaches programs can use to optimize SCEs, according to experts from across the academy. Though some items are very specific, there are opportunities for individualization based on program priorities.Aleda M H Chen
- Canadian Spine Society: 24th Annual Scientific Conference, Wednesday, February 28 - Saturday, March 2, Fairmont Chateau Whistler, Whistler, B.C., Canada November 13, 2024No abstractAntoine Dionne
- Management of factor Xa inhibitor-related traumatic non-intracranial bleeding events with andexanet alfa or four-factor prothrombin complex concentrate in a US multicenter observational study November 11, 2024CONCLUSION: This analysis provides insights into the clinical characteristics and management strategies, including time to treatment, for patients treated with andexanet alfa or 4F-PCC while hospitalized for FXa inhibitor-related traumatic bleeds.Paul P Dobesh
- Sex Disparities in the Use and Outcomes of Septal Reduction Therapies for Obstructive Hypertrophic Cardiomyopathy November 11, 2024CONCLUSIONS: Our results suggest that female patients were slightly more likely to undergo SRT, especially alcohol septal ablation. In-hospital mortality and postprocedural complications were similar between the sexes, but women received more pacemaker implantation and less ICD implantation.Carlos Diaz-Arocutipa
- A systematic review of reporting and handling of missing data in observational studies using the UNOS database November 9, 2024CONCLUSIONS: Merely a third of the identified UNOS database studies reported how they handled missing data in their analysis, with strategies varying. Although no singular approach to handling missing data exists, methods are available that can improve upon the most used approaches. Future best practices should include explicit reporting of missingness, detailed methods, and sensitivity […]William L Baker
- Falls and fractures in men with prostate cancer taking second-generation androgen receptor antagonists: A retrospective chart review October 22, 2024CONCLUSION: The prevalence of falls and fractures in patients receiving enzalutamide were higher in this retrospective chart review than reported in clinical trials and post-marketing studies. This could be due to the small patient population or the patient's comorbidities such as osteoporosis, bone metastases, or neuropathy. Fall/fracture risk with enzalutamide and other risk factors for […]Morgan Dennison