Recent publications
- Corticosteroid use beyond 1-year post heart transplantation is associated with worse outcomes: A contemporary analysis of the ISHLT registry March 27, 2025CONCLUSIONS: Steroid use beyond 1year post heart transplant was associated with significantly lower survival, and worsened morbidity among adult recipients. Whether this observation indicates steroid use is a marker of higher risk or worsens prognosis warrants prospective investigation.Abhishek Jaiswal
- Standard Instructions and Counseling for Naloxone Insufficient in the Era of Xylazine and Medetomidine Adulteration of Illicit Opioids March 20, 2025No abstractPriya Datta
- OLGA and OLGIM staging systems on the risk assessment of gastric cancer: a systematic review and meta‑analysis of prospective cohorts March 19, 2025CONCLUSION: Higher stages in OLGA and OLGIM systems are associated with a significantly increased risk of developing HGD and GC, validating these scoring systems for the assessment of GC risk and the design of endoscopic surveillance programs.Harold Benites-Goñi
- Clinical Profile and Treatment Patterns in Individuals with Type 2 Diabetes and Chronic Kidney Disease Who Initiate a GLP-1 Receptor Agonist: A Multinational Cohort Study March 19, 2025CONCLUSIONS: During 2012-2021, GLP-1 RA use steadily increased across multinational cohorts of patients with T2D and CKD, and persistence with treatment was high. GLP-1 use was independent of CKD severity.Manel Pladevall-Vila
- Real-world andexanet alfa utilization and the association between delay in administration due to hospital transfer and all-cause inpatient mortality March 10, 2025CONCLUSION: Delay in administering andexanet alfa due to hospital transfer may be associated with increased all-cause mortality.Huiqiao Fan
- Approaches for Embedding Structural Competency and Social Determinants of Health in Pharmacy Curricula March 3, 2025There is emerging scholarship related to teaching social determinants of health (SDOH) in pharmacy education; however, challenges remain for pharmacy educators due to a lack of formal consensus on which aspects of SDOH should be taught or evaluated. SDOH is often confused with similar, overlapping concepts such as cultural competence, cultural humility, Diversity, Equity, and […]Tyler Marie Kiles
- Renal Denervation Effects on Blood Pressure in Resistant and Uncontrolled Hypertension: A Meta-Analysis of Sham-Controlled Randomized Clinical Trials March 1, 2025CONCLUSION: RDN significantly reduced several SBP and DBP outcomes versus sham without significantly increasing complications. This makes RDN a potentially effective alternative to medications in URH.Hamidreza Soleimani
- The Burden of Hospital Illness Associated with Disseminated Versus Isolated Pulmonary Coccidioidomycosis in the United States February 25, 2025There are scarce data comparing inpatient mortality, length of stay (LOS) and all-cause hospital costs in disseminated coccidioidomycosis (DCM) vs. isolated pulmonary coccidioidomycosis (IPCM). We assessed the burden of hospital illness associated with DCM versus IPCM. This study was performed using National Inpatient Sample data from 2019 to 2021. DCM was defined as having a […]Craig I Coleman
- Impact of weight loss surgery on valproic acid levels: A case report February 20, 2025Weight loss surgery has become more common in the United States because of the increasing rates of obesity. The physiological changes caused by weight loss surgery have the potential for clinically significant changes in the pharmacokinetic parameters of mood stabilizers, including valproic acid (VPA). A patient with a history of Roux-en-Y gastric bypass and bipolar […]Kristin Waters
- Initiating buprenorphine to treat opioid use disorder without prerequisite withdrawal: an updated systematic review February 20, 2025CONCLUSION: The prevalence of buprenorphine dosing strategies that aim to omit POW has vastly increased over the past 4 years. While quality of evidence remains low, the increased quantity of publications and integration into health-system guidelines and protocols demonstrates the need for prospective, controlled studies. It is unknown how selection bias impacts current findings, further […]Kathleen K Adams
- Antifungal therapy patterns, healthcare utilization, costs, and mortality in central nervous system and non-central nervous system disseminated coccidioidomycosis across the continuum-of-care February 8, 2025OBJECTIVES: This study aims to describe baseline characteristics, antifungal treatment patterns, healthcare utilization, costs, and mortality in patients with central nervous system (CNS) and non-CNS disseminated coccidioidomycosis.Fariba Donovan
- The Impact of Ketamine-Based Versus Non-Ketamine-Based ECT Anesthesia Regimens on the Severity of Patients' Depression and Occurrence of Adverse Events: A Systematic Review with Meta-Analysis February 6, 2025CONCLUSION: Ketamine is a promising anesthesia adjunct to ECT that may enhance antidepressant effects in exchange for more adverse events.Dakota J Sicignano
- Interrupted versus uninterrupted anticoagulation for cardiac rhythm management device insertion January 28, 2025BACKGROUND: Guideline-recommended strategies to interrupt chronic anticoagulation with warfarin or direct oral anticoagulants (DOAC) during the perioperative period of cardiac implantable electronic device (CIED) surgery differ worldwide. There is uncertainty concerning the benefits and harms of interrupted and uninterrupted anticoagulation in patients undergoing CIED surgery.Brett Chen
- Suggested Dosing of Select Beta-lactam Agents for the Treatment of Antimicrobial-Resistant Gram-Negative Infections in Children January 23, 2025The Infectious Diseases Society of America (IDSA) publishes annual guidance on the treatment of antimicrobial-resistant (AMR) gram-negative infections. Within the AMR guidance, suggested dosages of antibiotics for adults infected with AMR pathogens are provided. This document serves as a companion document to the IDSA guidance to assist pediatric specialists with dosing β-lactam agents for the […]Christine R Lockowitz
- Association Between the Need to Change Initial Antifungal Therapy and Treatment Costs in Patients With Invasive Aspergillosis January 20, 2025CONCLUSIONS: Changing antifungals was associated with longer hospital stays and costs and higher all-cause costs over 12-months.Barbara D Alexander
- Prognostic Value of Frailty in Patients With Takotsubo Cardiomyopathy January 16, 2025CONCLUSIONS: Our results suggest that frailty is useful as a prognostic factor for in-hospital events in patients with TCM.Carlos Diaz-Arocutipa
- Diagnostic models to differentiate Takotsubo syndrome from acute coronary syndrome: A systematic review and meta-analysis January 14, 2025CONCLUSION: Our review identified multiple diagnostic models to diagnose Takotsubo syndrome. Although most models showed acceptable-to-good discriminative performance, calibration measures were almost unreported and the risk of bias was a concern in most studies.Carlos Diaz-Arocutipa
- Effect of Mediterranean Diets on Cardiovascular Risk Factors and Disease in Overweight and Obese Adults: A Systematic Review and Meta-Analysis of Randomized Controlled Trials January 9, 2025We systematically evaluated effects of Mediterranean diets (MED) on cardiovascular (CV) disease and risk factors in overweight or obese adults. Five engines and two registries were searched until October 2023 for randomized controlled trials (RCTs) evaluating any type of MED compared to other diets or advice in adults. Outcomes of interest were clinical outcomes and […]Adrian V Hernandez
- Assessing the Alignment Between Pharmacists' Reported Tasks and Employer-Advertised Skills January 1, 2025CONCLUSION: The fact that prescription review remains the top task from O*NET over the past 10 years and the top advertised skill in Lightcast is patient care underscores the contemporary misalignment and highlights a potential discrepancy in the emphasis of pharmacy education.Amy L Ives
- Examining the Alignment of Pharmacists' Daily Tasks, Employer-advertised Skills, and the Entrustable Professional Activities January 1, 2025CONCLUSION: Prescription processing, legal compliance, and operational pharmacy management are the most essential daily functions of today's pharmacists, contrasting with the person-centered nature of the EPAs. Amid the curricular evolution that has occurred to meet the future vision of pharmacy practice, programs must, nonetheless, continue to teach the skills required for the existing marketplace to […]Diana M Sobieraj