Research

Raman Bahal NDD PTM
Research Focus: New delivery strategies for synthetic nucleic acid analogues, develop novel gene correction based reagents. Selectively target oncogenic microRNAs for cancer therapy, and other microRNAs for treating genetic metabolic disorders. Bahal Lab

Quanying Bao NDD PTM
Research Focus: Formulation design and manufacturing (ointments, long-acting injectables, intrauterine systems, hydrogels, liposomes, pellets),in vitro and in vivo performance, targeted drug delivery, controlled and sustained drug delivery.

Robin Bogner PTM
Research Focus: Freeze-drying process modeling and optimization, formulation and performance of pharmaceutical solids -- both freeze-dried parenterals and oral dosage forms, amorphous drug solubility, reconstitution of lyophilized protein therapeutics, stability of compounded preparations.

Diane Burgess NDD PTM

Research Focus: Drug delivery (microspheres, nanoparticles, liposomes, emulsions, hydrogels); in vitro and in vivo performance testing; continuous manufacturing of complex parenterals; implantable sensors for metabolic monitoring. Burgess Lab

Bodhi Chaudhuri PTM
Research Focus: Pharmaceutical Technology, Multi-Scale Modeling of Pharmaceutical and Biomedical Systems, Transport Phenomena in Complex Fluids, Discrete Element Method, Powder Technology, and 3D printing. Chaudhuri Lab

Antonio Costa NDD PTM
Research Focus: Continuous manufacturing approaches for nanoparticle drug products, including GMP system design; Formulation and development of nanoparticles (e.g. liposomes, LNPs and polymeric micelles); Analytical techniques for nanoparticle characterization.

Na Li NDD PTM

Research Focus: Oral drug delivery, enabling formulation and process development of poorly-soluble drugs, interactions with the human gastrointestinal environment including the gut microbiome. Li Lab

Xiuling Lu NDD PTM BMI
Research Focus: Formulation development, characterization and assessment, drug delivery systems, multifunctional nanocarriers for improved cancer therapy, theranostic nanomedicine. Lu Lab

Brian Aneskievich BMP
Research Focus: Molecular pharmacology of cell membrane and nuclear receptor signaling control over regulation of gene expression relevant to chronic inflammatory diseases, defects in differentiation, and cancer proliferation.

David Grant DMM
Research Focus: Development of analytical and computational tools that allow high-through-put chemical structure determination. These tools advance research in metabolomics, biomarker identification and drug design.

José Manautou DMM MT
Research Focus: Identification and characterization of novel genetic determinants of susceptibility to chemical hepatotoxicity, regulation of liver transporters, chemical models of hepatoprotection.

Theodore Rasmussen DMM MT EN
Research Focus: Personalized medicine, stem cell research, and epigenetics as related to cholesterol dysfunction, birth defects, and reproductive biology.

Gregory Sartor DMM BMP EN DDD
Research Focus: Animal models of drug addiction; epigenetics, cell type-specific analysis, and drug discovery.

L. Cody Smith MT BMP
Research Focus: Air pollution and respiratory system toxicology, immunology and inflammatory signaling mechanisms, sex steroid signaling and sex differences in inflammation, mouse models.

Xiaobo Zhong EN BMI
Research Focus: Mechanistic roles of long non-coding RNAs in postnatal liver maturation, alteration of drug metabolism in adults by drug exposure at early life, interindividual variations on drug metabolism and personalized medicine.

Chat Abeywickrama BMI DDD
Research Focus: Development of small-molecule fluorescent dyes for biomedical imaging and diagnostic applications, fluorophore-guided drug delivery and trafficking, and (bio)chemical sensing dyes.

M. Kyle Hadden DDD
Research Focus: Early stage drug development focusing on the design, synthesis, and evaluation of small molecules as therapeutic agents for the treatment of cancer. Hadden Lab

Hunmin Jung DDD
Research Focus: Structure-guided development of: 1. anticancer agents targeting DNA lesion repair and de novo nucleotide biosynthesis pathways; 2.  modulators that inhibit or enhance the incorporation of non-natural nucleotides into DNA or RNA; 3. antidiabetic agents/biomarkers targeting glucose sensing transcription factors; 4. antibacterial/antiviral agents targeting DNA repair/bypass and nucleotide metabolism. Jung Lab website under development. Jung Lab

Olga Vinogradova DDD
Research Focus: Structural Biology, Protein-Protein/Protein-Ligand Interactions, Rational Drug Design, Integral Membrane Proteins and Across-membrane Signal Transduction, Nanodiscs, NMR. Vinogradova Lab

Andrew Wiemer DDD BMP
Research Focus: Discovery of drugs and drug targets related to cancer and immunology. Wiemer Lab

Dennis Wright DDD
Research Focus: The design, synthesis and development of small molecule therapeutics primarily for the treatment of infectious disease and cancer.